multiple-sclerosis-treatment

Stem Cells for Multiple Sclerosis MS PLS Therapy

Updated January 20, 2017 – MS or Multiple sclerosis is also called disseminated sclerosis or encephalomyelitis disseminata. MS is a disorder where the myelin sheath around the axons of our brains and spinal cord are damaged, leading to demyelination and scarring in addition to a comprehensive spectrum of indications and symptoms that are commonly referred to as Multiple sclerosis.

What is MS? – VDO

Over time, MS changes the ability of nerve cells and the spinal cord to communicate with each other. Nerve cells generally communicate by sending electrical signals down long fibers known as axons. Axons are wrapped in an insulating reparing-myelin-sheath-damage-thailandbio-material called myelin. In MS, our body’s own immune system attacks and damages the myelin sheath. When our myelin is lost, axons can no longer efficiently conduct signals or communicate as they normally do.(21591539)

The term sclerosis refers to scars, plaques or lesions in the white matter of our brain and spinal cord that is primarily composed of myelin. Although we know much about the mechanisms and symptoms or this degenerative disease, the causes of MS still remains relatively unknown. There are several neurological symptoms that can appear with MS disorder, and frequently the symptoms progress to display severe physical and cognitive impairment. New symptoms can occur rapidly or occur slowly over time. The slow appearance of symptoms is known as progressive Multiple sclerosis. The symptoms of MS can sometimes go away entirely on their own but can also lead to irreversible neurological degeneration particularly in progressive MS.(21721432)

Neurological testing can help identify the disorder whose primary features are: myelinolysis in patients brains and spinal cord. The demyelinating disease primarily affects the “CNS” or central nervous system. A well known type of de-myelinating disease is known as Multiple sclerosis or MS.(24192520)

Categorization of MS Disease:

  1. MS or Multiple Sclerosis
  2. Acute multiple sclerosis
  3. Persistent cerebral cord sclerosis
  4. Balo concentric diffuse cerebral sclerosis
  5. Diffuse cerebral sclerosis – Schilder’s disease
  6. Inflammation of Optic nerve myelin  – Devic’s disease
  7. Acute disseminated encephalomyelitis
  8. Necrotizing hemorrhagic encephalitis – Sub-acute and Acute

4 Variations of Multiple Sclerosis with Stem Cells:

  1. RRMS or Relapsing Remitting Multiple Sclerosis:  The most common type of MS we treat. RRMS symptoms include repeat attacks with progressive loss of nerve functions after each attack, followed by a period of remission where normal function is partially or restored totally restored without flareups or Exacerbations.
  2. SPMS or Secondary Progressive Multiple Sclerosis Stage:  SPMS usually follows RRMS after continued attacks. This stage results in progressive neurological damage that is associated nerve demyelination.
  3. PPMS or Primary Progressive Multiple Sclerosis:  This stage represents a steady decline with no intermittent remissions, exacerbations or Flare Ups
  4. PRMS or Progressive Relapsing Multiple Sclerosis Stage: PRMS is the rarest type of MS that affects people and the most difficult to treat. Most patients will not qualify for stem cell transplants and the patients that are are usually recommended an aggressive cell protocol as part of a combination therapy that includes Immunosuppressive techniques to slow down the rapidly progressing condition.

MS is amongst the most serious and difficult nervous system disorders to treat that we have today in the field of regenerative medicine. MS Disorder normally invades specific regions of the human nervous system, causing intense exhaustion along with other symptoms and clear physical signs that can be readily identifiable using MRI or Brain CT Scans.

Clinical indications of MS include:symptoms-of-MS

  • Nystagmus
  • Motor weakness
  • Visual impairments
  • Limb paresis or paralysis
  • Diplopia
  • Peripheral neuropathic Pain
  • Ataxia
  • Motor Neuron Disease MND
  • Bladder dysfunction and urinary incontinence

Lab evaluation for MS usually require detailed cytology of the patients cerebrospinal fluid, along with detailed protein analysis and Radiographic examinations such as MRI or CT Scan around the encephalocoele. Radiographic exams look for multiple and/or isolated lesions in the brain. Nearly half of the patients we treat for MS using allogenic,amniotic neural,interferon Beta and Hematopoietic stem cells show improvement shortly after treatment while some patients show continuing improvement that lasts over a few years.

stem-cells-repair-multiple-sclerosis

Stem Cell Transplants to Treat Multiple Sclerosis

The Regeneration Center of Thailand has developed a multistage program to treat MS. Nerve stem cells and neurons are able properly regenerate damaged areas of nerve myelin and axons while mesenchymal stem cells help to reverse any autoimmune damage. This alone can help can slow down, stop or even reverse the progressive nature of MS while the enriched neural cells can target the brain lesions that exist.

TREATMENT PRECAUTION
Please Note That Not All Patients Qualify for Treatment of Degenerative Neurological conditions such as MS. Patients with late stage, severe underlying conditions or travel restrictions may not qualify for the 2-3 week treatment protocol in Bangkok.

Treatment Overview


Total Number of Cell Treatment: : 2-8 Infusions of clinical-grade Multipotent mesenchymal Stem cells (per Treatment stage requirement)

Type of Injections: Most patients with early stage MS will require will require enhanced stem cells. For patients with progressive MS a more aggressive combination treatment plan will be required using Allogeneic derived cells from matched Cord blood, Amniotic Membrane and/or Placenta cells are required for most cases. Our cell infusions are done over multiple dates and do not require invasive surgery. The cells are target delivered via a Guided CT Scanner (when necessary) or more commonly through an Intravenous Drip,Direct injection and/or Intrathecal Injections.

Physical Rehabilitation Post-Therapy: Physical Rehabilitation therapy for MS in Bangkok is optional depending on the patients travel/time constraints. Complete physical rehabilitation post-therapy and can be provided upon request for 2-5 hours per day and up to 5 days per week. 
Medical visas and extended stay accommodations for the patients and family can also be included upon request.

Costs for the MS Treatment

Due to the varying degrees of existing medical conditions and the stage of degeneration, our medical team will need to review the potential candidates current and actual medical condition before a treatment protocol can be established. Upon acceptance, we can provide a more accurate assessment of the patient condition and what we expect to achieve post-therapy. The final plan will include the a day by day treatment outline with total number nights required along with the total and fixed medical related expenses (excluding accommodations or flights). Stem Cell Therapy for MS using MSc cells will require a minimum of 14-21 nights in Bangkok.  To begin the qualification process for our multi-stage MS Treatment protocol please prepare your recent medical records such as Brain MRI’s,CT Scans or PET Scans (Preferred ) and contact us today.

To learn more about Treatment for Multiple Sclerosis with Stem cells please contact us today.

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Published Clinical Citations

Comments 8

    1. Post
      Author
  1. I would greatly appreciate it if anyone could give me any cost estimate for the initial and follow-up treatments with stem cells, including PT, if possible?

    I’m 63, male, have had SPMS Secondary progressive multiple sclerosis since diagnosis in 1986, and tried practically every available treatment, particularly any targeting SPMS.

    My sincerest thanks for any assistance you may provide.

  2. I am 67 years old, diagnosed in 1992 with RRMS. In 2009 it had become SPMS. I walk with a cane, swim 5 days a week, take Pilates for MS twice a week, am slim and fit. Am I a candidate for your stem cell procedure?

  3. I seem to have blockage of blood vessels in the brain and spine which led to diagnosis of Chronic Cerebrospinal Venous Insufficiency (CCSVI). This is a big problem for me as my fatigue and lightheadedness are becoming more and more frequent. I have read that stem cells have helped people with MS reduce their fatigue and promote new blood vessels with angiogenesis. Is this true? can you please help me manage my MS symptoms?

  4. I am from The U.S.A. and I have secondary progressive. Ms. First dx in 2003, I am now having severe balancing and mobilization disability that began about 18 months ago. I am 57 years old and i want help. Can you help me please?.I am living in Bangkok with a retirement visa. I want stem cell therapy. How Can I Arrange For this. Thank you very much.

  5. Are there any dangers with stem cells therapy for SPMS? how do you match the stem cells to the patients? I was diagnosed 2 years ago and my last MRI showed a big increase in new lesions.about 29 in total. I have tried Tysabri,Copaxone and Transcranial magnetic stimulation but nothing seems to be working. Please contact me so i can send you my recent checkup.

    1. Post
      Author

      Hello Mr Crawley, The cells are HLA matched (HumanLeukocyte Antigens) to the patient to ensure compatibility. We have emailed you the information requested.

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