Hip Injury, Pain &
Avascular Necrosis

The Regenerative Centers’ orthopedic stem cell protocols are an investigational option that some people with degenerative hip conditions, injuries and arthritis consider alongside standard care, and they are not a proven substitute for hip replacement surgery. Alongside care for knee injuries, knee arthritis and hand and wrist problems, our non-surgical stem cell-based treatment is offered to some adults with chronic hip pain from a variety of causes, such as:

• Avascular necrosis
• Autoimmune Rheumatoid arthritis and Hip Osteoarthritis
• Osteonecrosis
• Hip injuries related to sports
• Hip bursitis
• Sarcopenia muscle loss
• Hip joint degeneration
• Hip disease due to ankylosing spondylitis
• Tendinopathy due to injury (tendon problems linked to Lupus are assessed by a rheumatologist)
• Labral tears and/or labrum tears

Stem Cell Therapy as a Non-Surgical Option for Hip Pain in 2026

Our hip and shoulder stem cell therapies are combined with PRP (platelet-rich plasma) and growth factors as a non-surgical, investigational option for some patients with cartilage damage or chronic hip pain, including some who are considering hip replacement surgery or hip resurfacing. Spine problems such as DDD and Spinal Injuries, and moderate femoral nerve pain, need separate assessment.[1] Our treatment protocol is mainly considered for mild and moderate cartilage damage and uses laboratory-expanded mesenchymal stem cell injections, either from the patient’s own cells (autologous, for mild conditions) or from donor allogeneic stem cells (for moderate to severe conditions). Early research suggests these cells may help reduce inflammation and pain, but they have not been shown to regrow cartilage or reverse arthritis in the hips or knees, and results vary from person to person.^[2]

Treat Hip Joint Injury & Repair AVN

Hip surgeries, such as replacement and resurfacing, are major operations used mainly for advanced arthritis or joint damage, and recovery involves several weeks to months of rehabilitation to rebuild strength and mobility.^[3]

Repair damage to injured tissue with Stem Cells

Our orthopedic stem cell hip treatment works by targeting the areas of arthritis or injury with both clinical-grade stem cells and ( PrP ) platelet-rich plasma. Cultured stem cells and paracrine cell signaling act as biological seeds, with tissue-specific growth factors that serve as fertilizers to strengthen cells and help quickly heal injured areas. Our unique 2-week treatment course uses isolated stem cells with Transforming Growth Factor-Beta (TGF-β) growth factors, Platelet-Derived Growth Factor (PDGF), Bone Morphogenetic Proteins (BMPs), Vascular Endothelial Growth Factor (VEGF), and Fibroblast Growth Factor (FGF), which are delivered to the patient on alternative cell infusion dates via the blood circulatory system. These additional steps in our treatment protocol are intended to enhance cell signaling over the course of treatment, although their added benefit has not been established in clinical trials. Our current research suggests that introduced cells act mainly through signals that may affect inflammation and repair, and they have not been shown to grow into new joints, tendons or ligaments. The Regeneration Center uses a proprietary closed-system UC-MSC+ cell culture to promote rapid stem cell development.

Avoid Surgery with Stem Cells & Regenerative Medicine

Regenerative medicine is a conservative treatment option and might not be the final answer for all patients with degenerative hip injuries and neuropathy. In sports medicine cases treated with UC-MSC+ stem cells, some patients report less pain and better function, but results vary, long-term evidence is still limited, and some patients will still need surgery such as total hip replacement. Our bone regeneration protocols are minimally invasive, and recovery time is minimal after treatment. Most patients report only slight soreness in the treated areas, with minimal bruising, for 24-48 hours post-therapy. All cells are tested before use, but like any medical procedure, cell injections can cause side effects, such as pain, swelling or infection at the injection site, and rarer reactions. After hip joint treatment, patients are encouraged to follow a hip osteoarthritis diet and engage in regular hip rehabilitation to help restore proper hip function. Hip stem cell treatment may be an option for some patients with mild to moderate conditions after a full medical evaluation, and it is generally not suitable for severe joint damage. Stem cell therapies using cells from your own body can also be repeated after 6-12 months (if necessary) to achieve optimal results for people with active lifestyles. For patients with severe hip damage, stem cell treatment alone might not be sufficient. For cases requiring core decompression or severe musculoskeletal conditions, we offer a unique treatment that combines microsurgery with stem cells (administered after surgery) and cell-specific growth factors to expedite and normalize the healing process, leading to faster recovery and a lower risk of scarring or hip arthritis.

Using Stem Cell Therapy for Hip Repair


Number of Cell Infusions for Hip arthritis and hip pain: 2-8 Targeted infusions of expanded Mesenchymal “UC-MSC+” Cells with tissue-specific growth factors for increasing formation of fibrocartilage fibers, growth factors & differentiated scaffolds.

Types of Stem Cells and Delivery Methods for Hip: Enhanced UC-MSC+ Mesenchymal cells & Hip regenerative therapy protocol will depend on the severity of the underlying degeneration, as needed. Most of our cell-enriched treatments do not involve open surgery, although some severe cases combine stem cells with surgery such as core decompression. The delivery of the cells is made via radio guidance (when necessary) or, more commonly, through the combination of Intravenous Drip, direct Local injections, Intra-articular Injections, Intraosseous Injections, Intrathecal Injections (if experiencing neuropathy), Ultrasound-guided (in office) or fluoroscopy-guided stem cell delivery (in a hospital setting only).

Rehabilitation Options Post-Treatment: Physical rehabilitation therapy is strongly recommended after treatment and can be provided in Thailand or upon return home. We offer optional in-person rehab packages based on your travel/time constraints. Our physical therapy and pain relief programs are available upon request for 2-3 hours per day and up to 5 days per week. Medical visas and hotel accommodations for the patient and family can also be provided upon request.

Total Treatment Length: The estimated treatment time for stem cell therapy for hip pain and degenerative hip arthritis is 10-14 days in Bangkok (depending on the severity of the underlying injury)

Looking to Relieve Hip Pain Naturally?

The Regeneration Center offers patients a comprehensive approach to hip joint injuries, and our team will discuss the possible benefits and risks of treatment compared with options such as hip replacement. We have treated professional athletes to average elderly patients who needlessly suffered through decades of chronic hip joint pain. If you or a loved one is suffering from a degenerative hip condition or chronic hip pain, or if you have any difficulty standing up or walking stairs, you may be a candidate for our procedure. To learn more, please contact us today.

What type of stem cells are used for hip injuries and avascular necrosis?

The protocol described uses mesenchymal stem cells, either the patient's own autologous cells for mild conditions or matched donor allogeneic cells for moderate to severe conditions. Cell sources named in the article include adipose tissue, bone marrow, peripheral blood, placental tissue and umbilical cord. The cell type and delivery method depend on how severe the hip degeneration is.

ArticleMesenchymal Stem Cell Isolation & Expansion of MSC+ CellsRead the article↗

Cost to Treat Hip Osteoarthritis w/ Stem Cells

Due to the varying degrees of injuries, our orthopedic team must conduct a medical review of all potential patients. This can be done online using the patient’s current medical records, such as Hip MRI or CT Scan, and reports from the patient’s orthopedic doctors. Once the treatment evaluation is complete, we can determine whether the patient is a good candidate and provide a detailed treatment plan with the total number of stem cell injections, the number of nights required, and fixed medical-related costs for the entire treatment.

Published Clinical Citations

[1] ^ Homma, Yasuhiro, Kazuo Kaneko, and Philippe Hernigou. 2013. Supercharging allografts with mesenchymal stem cells in the operating room during hip revision. International orthopaedics, no. 10 (December 10). doi:10.1007/s00264-013-2221-x. https://www.ncbi.nlm.nih.gov/pubmed/24323352

[2] ^ Houdek, Matthew T, Cody C Wyles, John R Martin, and Rafael J Sierra. 2014. Stem cell treatment for avascular necrosis of the femoral head: current perspectives. Stem cells and cloning : advances and applications (April 9). doi:10.2147/SCCAA.S36584. https://www.ncbi.nlm.nih.gov/pubmed/24744611

[3] ^ Rungsiyanont, Sorasun, Nirada Dhanesuan, Somporn Swasdison, and Shohei Kasugai. 2011. Evaluation of biomimetic scaffold of gelatin-hydroxyapatite crosslink as a novel scaffold for tissue engineering: biocompatibility evaluation with human PDL fibroblasts, human mesenchymal stromal cells, and primary bone cells. Journal of biomaterials applications, no. 1 (February 22). doi:10.1177/0885328210391920. https://www.ncbi.nlm.nih.gov/pubmed/21343214