Stem Cell Treatment Pulmonary Fibrosis – ILD IPF & Lung Scarring

Updated February 05, 2019 – Pulmonary fibrosis is the thickening and scarring of the lung tissue. The term idiopathic means that the cause of the disease is unknown. Though it is not completely understood what causes idiopathic pulmonary fibrosis, the disease process is well-explained in various medical literature and case history.(25039426)

Treatment of IPF with Stem Cells

IPF and fibroid lung disease usually starts with a presence of inflammation in the alveoli. The alveoli are the tiny air sacs in the lungs where the exchange of carbon dioxide and oxygen happens. The very thin lining of the alveoli allows this gas exchange. Once these alveoli become inflamed and damaged in some way, the body’s reaction would be to activate the immune response and to heal the damaged alveoli.(25986617)

This causes scarring and thickening of the alveolar walls. Unfortunately, the thickened and scarred alveoli cannot perform efficiently during gas exchange. This ultimately leads to lesser amount of oxygen that can be transported into the body and less carbon dioxide that can be expelled out.

Primary Risk factors for IPF

the most common predisposing factors of developing idiopathic pulmonary fibrosis are:

  • Cigarette smoking
  • Exposure to various pollutants
  • Viral infections
  • GERD (Gastroesophageal reflux disease). This is when the stomach contents of a patient go back to the esophagus. There is a risk of aspiration of these stomach contents into the trachea which can in turn cause lung infection.(26593230)
  • Inflammatory bowel diseases such as ulcerative colitis and crohn’s disease

Signs and Symptoms for IPF Lung Failure


Some of the common signs and symptoms that are present in patients diagnosed with onset idiopathic pulmonary fibrosis are:

  • Severe shortness of breath. This is caused by heart disease or the decreased amount of oxygen that the body gets due to the inefficient, affected alveoli. This gets worse with physical activity since the body is trying to get more oxygen.
  • Constant Dry cough.
  • Clubbing sensations of the finger and toenails. Clubbing is the swelling in the base of the finger. This is usually accompanied by cyanosis which the bluish discoloration of the nails. This is a sign of hypoxia or decreased level of oxygen in the tissue. This sign usually manifests later on the disease progress.
  • Easily being fatigued

Traditional vs Modern Treatments for Lung Fibrosis

There were traditionally very limited options for treating a progressive degenerative diseases such as COPD and idiopathic pulmonary fibrosis. No pharmaceutical medication based cures are available to treat this disease today. In some cases, steroids are prescribed to help decrease the inflammation but the effects are temporary and does nothing but mask the illness. Lung transplants are an option for some but are considered very invasive and dangerous in nature.  Lung transplants are very risky and is usually only offered in advanced stage patients. The alternative to lung transplants is non-surgical stem cell treatment for Idiopathic Pulmonary Fibrosis.(25412619)

Healthy vs Diseased Lungs

Diagnosing Idiopathic Pulmonary Fibrosis

After going through a thorough physical exam and health history taking, some of the diagnostic procedures that can confirm a diagnosis of pulmonary fibrosis are:


  • Chest X-rays or CT Scans: The doctor may see a pattern of opacities in a patient’s X-ray which can be caused by the thickened and scarred lung tissues.
  • Pulmonary function test: a test done to measure the patient’s breathing capacity.
  • Arterial blood test: to examine the ability of the lungs to move oxygen into the tissues of the body.
  • Lung biopsy: getting a sample of lung tissue and studying the sample to identify areas of scarring and thickening.

Stop Lung Disease & Lung Failure

Your Stem cells is essentially the bodies pharmacy. Stem cells are are the building blocks of your entire body. These types of potent cells are called “totipotent” cells as they are able to change/differentiate into any type of cell,tissue or bone in the human body. The Stem Cells for Treating Pulmonary Fibrosis, focused on the destroyed or limited lining of the alveoli that is at the root of the issue. (25896401) For various reasons (Cigarette smoking,Viral infections,genetics) the bodies natural ability to regenerate is being blocked causing the types of complications that manifest themselves as diseases and degenerations.


Our treatment for IPF using isolated & enhanced lung stem cells seeks to re-promote natural healing of the previously damaged alveoli cell and lining. The goal of our stem cell treatment for idiopathic pulmonary fibrosis is to assist the body in regenerating new healthy tissues and/or blood vessels through a process called angiogenesis. Our lung cell treatment offers effective regeneration and replacement of the lung tissue affected by fibrotic scarring and honeycombing through increased levels of myofibroblasts

Please Note That Stem Cell Treatments for IPF and Chronic Lung Diseases are not appropriate for all patients. Those with multiple conditions, late stage or travel restrictions due to need for constant Oxygen tanks may not qualify for the 2-3 week treatment protocol we offer. Please contact us for details.


Multi-Stage Lung Cell Delivery

Interstitial lung diseases pose a significant challenge for pulmonologists and lung bioengineering. Diseases such as asthma, Idiopathic pulmonary fibrosis, lung cancer treatment, COPD, Cystic fibrosis, emphysema & hyaline membrane disease are just some of diseases that can be managed effectively via lung stem cell therapies. Due to the complexity and locations of the diseased regions it has always been very difficult to effectively deliver cell therapeutic agents. Fortunately, the Regeneration Center has developed a combination delivery method to target the diseases from multiple vectors (depending on the patient’s needs) including guided radiography (when necessary), Intravenous, direct injection, Intrathecally and now for the first time via Intranasal inhalation for a painless and effective delivery of endogenous lung progenitor cells, lung epithelial stem cells to both the airway and vascular system of the lungs.


The Regeneration Center has developed a combination delivery method to target the diseases from multiple vectors (depending on the patient’s needs) including guided radiography (when necessary), Intravenous, direct injection, Intrathecally and now for the first time via Intranasal inhalation stem cell therapy for a painless and effective delivery of endogenous lung progenitor cells, Lung epithelial stem cells to both the airway and vascular components of the lungs.

 IPF Lung Treatment Protocol

Total of Stem Cell Infusions Required: 2-8 Infusions of Clinical Grade Enriched MSc+ Lung Cells. ( Multiple stages may be necessary for severe cases )

Method of  Cell Delivery: Due to the progressive degenerative nature of the disease, most patients will require enhanced cell transplants derived from immuno-compatible allogeneic cells.  For patients with multiple simultaneous issues or severe respiratory failure an aggressive combination treatment will be required. The isolated and expanded cells used are pre-screened for Infectious Diseases, sterility and strength. For patients with severe respiratory failure an aggressive combination treatment will be required.

Post-Treatment Lung Rehabilitation: Pulmonary Rehabilitation Services is optional but is highly recommended after any treatment. For patients with the option to stay in Thailand, we offer complete integrative rehabilitation program in partnership with Bangkok Hospital or Bumrungrad international hospital in Bangkok. Pulmonary rehabilitation is also beneficial for patients who are experiencing severe difficulty in breathing. Smoking is also greatly discouraged for patients with this condition and active smokers will not qualify for our treatment.  The rehabilitation packages in Bangkok are available to all candidates as needed (2-5 hours per day, 6 days per week)
. Medical treatment visas and hotel accommodations for long term stays can also be provided upon request.

Due to varying degrees of respiratory diseases our pulmonary specialists will need to better understand the patients needs to qualify any potential candidates. Our initial review can be done online and takes around 7 business days for the medical assessment. Suitable candidates for the our treatment for IPF with Stem Cells will require a minimum of 2-3 weeks in Bangkok. To begin the qualification process please prepare your recent pulmonary tests such as spirometry exams, lung function tests and radiology scans from an MRI or High Resolution Chest CT Scans and contact us today.

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Published Clinical Citations



  • Hello, guest
  • My Father is 80 years old and just diagnosed with IPF.  He has always been VERY active.  I would like more info on stem cell treatment at your clinic.  What is the cost?  How long will the stay be generally?
    • Support Team
      Hello Donna, Thank you for contacting the Regen Center. We have emailed you more information about treatment for your fathers lung disease (IPF)
  • I have been diagnosed with Idiopathic Pulmonary Fibrosis in July 2018, they gave me 12 months and I would like to find out about receiving stem cell treatment at your clinic.Costs ETC
  • Hello, my mother is diagnosed with ILD(ANA/anti RO+)@ CKD having trouble in breathing and lower oxygen levels while on routine household activities. I would like to know if you can help on any available treatment for her. And what would be the approximate time of treatment and cost. Thank you.
    • Support Team
      Hello Mr Kharpude, Thank you for contacting the Regen Center. We have emailed you more information about treatment options for your mothers interstitial lung disease.
  • Hello, I would like to have more information from pulmonary fibrosis, my father is in the begin of this disease, I will like to know if you have some treatment. Thank you
    • Support Team
      Hello Mr Castillo, Thank you for contacting us about your treatment for your fathers lung disease (pulmonary fibrosis) . An email was sent to you with the information requested.
  • How much does this lung disease treatment cost? My dad was diagnosed with IPF about a year ago. He  is 68 yrs old. 
  • Hi, my father have been diagnosed with Idiopathic Pulmonary Fibrosis and would like to find out about receiving stem cell treatment at your clinic. Do you collaborate with a hospital in Greek or a Greek doctor? Thank you in advance for your reply.
    • Support Team
      Hello Mrs Ioanna, sorry we do not have a treatment in Greece or have Doctors who speak Greek. We can offer assistance in English and Thai only.
  • I have been diagnosed with Idiopathic Pulmonary Fibrosis and would like to find out about receiving stem cell treatment at your clinic.
  • Hi, i am a 40yr old from New Zealand and i have A1ATD, I was a smoker and have now stopped, but alas damage was already done. At the moment i struggle to walk more then 40M without running out of air. I am wondering if you are able to help get my lung function better. I was a very active person before my lings gave out, I was a martial arts teacher. Cheers
  • My husband has been diagnosed with IPF and has been on oxygen therapy for over a year .Would he qualify for stem cell therapy? He is 84 years old but has always been very active - was still working until 2 years ago .He is desperat to get back to work!Please let me know what other information you require
  • looking to have stem cell therapy for damaged lungs. Dad was diagnosed 2 years ago. recent respiratory test show 80% in one lung and 75% in the other. can send you all tests.Can stem cell therapy cure IPF?
  • Good day.I am Jedd Cruz. My mom is diagnosed with IPF. I understand there is no cure, so am desperate to seek some help. Would you be able to send me additional info on how the arrangement for treatment is done? Thank you.
  • My Brother was just diagnosed with IPF and lung failure. We did tests to make sure and its not genetic but my mother also had Interstitial lung disease. She had a lung transplant back in 2006 and ended up dying from complications from it in 2010. Its a terrifying and terrible disease. We are now exploring alternative treatments and cell therapy is on top of our list. Did want to ask though s there a way to shorten treatment time?
  • Hello, I had an accident in Germany and had a CT scan , The German Dr. found a shadow on my right lung. So when i went back to the USA. I told my doctor to do a new CT scan . The Dr said , Nothing has changed , still a shadow on the right lung. So make sure my lung is clean and clear , sinus too. I do exercise for my lungs . to help stay strong. The Dr says i have Bronchiatasis . So then i read about stem cell research . I went to another Dr in Denver Colorado . He took bone marrow out of my hip , but said it was not good to inject because of little clots.He said my blood clots fast . He tried again and the same happened again . I will see my family Dr . on thursday . I am wondering if you know of a better way to help me. I do not have a cough , I am not out of breath , I exercise , The doctor says it was because i was sick as a child. I do not smoke. But i would like to repair my lung ... it is two little spots on the right lung.
  • hello everybody.......... i was diagnosed of idiopathic pulmonary fibrosis (IPF) 2015 and my 2 medications are not help me slow down the progression of IPF which was pirfenidone and nintedanib,so i chose Pirfenidone helps to slow the development of scarring in the lungs by reducing the activity of the immune system.i spent a lot of money taking this medication and herbal medicine but my condition get worse every month. Can stem cell therapy help repair my lung tissues?
  • Can your treatment help small holes in lungs. I am not a smoker and diagnosed with mild emphysema possible exposure to fungus pulmonary doc says
  • What kind of results have you had with this treatment? Does it reverse the scarring? If the lungs regenerate, does the fibrosis continue?thank you
  • My wife was diagnosed with idiopathic pulmonary fibrosis in January after being sick for over 2 years. Our doctors have told us that the disease in in terminal stage and they believe she has less than 6 months to live. I don't know what to do. We don't have insurance and really need some support and guidance from someone. Our doctors are not being very helpful and have told us that they cannot do anything other than increase her dosage of Nintedanib which has not done anything. Is my wife a candidate for stem cells?
    • Support Team
      Thank you for contacting us about treatment for your wifes condition. Please note terminal stage patients normally require constant supply of oxygen and are severely limited in travelling. It would be best to work with a pulmonary specialists in your home and have emailed you the information requested.
  • Support Team
    My wife was diagnosed with pulmonary fibrosis last year. We went to University in Spain to see some lung specialists but it seems that her lungs are so bad and she also has diabetes type 2 so she did not qualify for the stem cell clinical trials. The doctors there recommended a lung transplant but we really do not want to do that. One of the patients there recommended we contact you to see if there were any option. We will Fax all her records to you next week. Please email us if you need anything more from us.