Induced Pluripotent Stem Cells

Gastrulation Germ Layer definition and formation in humans

Stem Cell Regeneration Center Glossary

The Germ layers consist of about three layers of cells: Ectoderm – exterior germ layer Mesoderm – middle germ layer Endoderm – internal germ layer These three distinct layers are formed after a blastocyst’s inner cell mass undergoes a process of specific organization called gastrulation,[1] which occurs after the blastocyst phase in embryonic development. Organization or Gastrulation [2] involves many things including distinct differentiation patterns …

Oligodendrocyte-Marker-Differentiation-and-Myelination

Oligodendrocyte Marker Differentiation and Myelination

Stem Cell Regeneration Center Glossary

Oligodendrocytes are particular useful types of cell for treatment in conditions such as ataxia,brain injuries,ALS,motor neuron disease and spinal cord damage. [1] Oligodendrocytes are also helpful for neural function in that it provides insulation through the myelin sheath. For instance, in our treatments of autoimmune diseases like multiple sclerosis, considerable damage in the myelin sheath may be damaged, which exposes the neural cell underneath …

MSCs-Progenitor-cells

Progenitor Cell Manipulation

Stem Cell Regeneration Center Glossary

Progenitor cells are the interim oligopotent cell formed during the differentiation process from stem cell state to the target cell variant. Progenitor cells are a subtype of stem cells that are more differentiated than pluripotent stem cells but still have the ability to differentiate into a limited number of cell types or lineages. Unlike pluripotent stem cells, which can differentiate …

Ectoderm-diagram-explanations

Ectoderm Derivatives and Endoderm

Stem Cell Regeneration Center Glossary

An Ectoderm is a body of cells forming the outermost layer of major organ systems in the body, such as the skin, neural cells and nervous system, and the sensory organs.  This layer is formed by the blastocyst’s inner cell mass.[1] The cells of various germ layers can differentiate themselves [2] through lab culturing to try to regenerate and repair diseased organs …

Stochastic-differentiations

Stochastic Differentiation Applications in Regeneration Therapies

Stem Cell Regeneration Center Glossary

Stochastic differentiation refers to the process in which a stem cell undergoes division, giving rise to two daughter cells that are differentiated.[1] On the other hand, another stem cell goes through the process of differentiation or mitosis to generate two stem cells that are similar to its original cell state, thereby maintaining stem cell number.[2] This process of differentiation is …

mesenchymal-stem-cells-therapy

Multipotent Mesenchymal Adult Stem Cells (MSCs)

Stem Cell Regeneration Center Glossary, Research

Mesenchymal (MSC) derived stem cells are the bodies own restoration system. Nature allows MSC cells to deliver a homing signal that helps recruit other stem cells in the body to mobilize and “fix” an injured area.  Researchers at Rosalind Franklin University of Medicine have recently reported that MSC Mesenchymal stem cells are much better prepared to begin the bodies natural …