Progenitor cells are the interim oligopotent cell formed during the differentiation process from stem cell state to the target cell variant. Progenitor cells are a subtype of stem cells that are more differentiated than pluripotent stem cells but still have the ability to differentiate into a limited number of cell types or lineages. Unlike pluripotent stem cells, which can differentiate …
Ectoderm Derivatives and Endoderm
An Ectoderm is a body of cells forming the outermost layer of major organ systems in the body, such as the skin, neural cells and nervous system, and the sensory organs. This layer is formed by the blastocyst’s inner cell mass.[1] The cells of various germ layers can differentiate themselves [2] through lab culturing to try to regenerate and repair diseased organs …
Stochastic Differentiation Applications in Regeneration Therapies
Stochastic differentiation refers to the process in which a stem cell undergoes division, giving rise to two daughter cells that are differentiated.[1] On the other hand, another stem cell goes through the process of differentiation or mitosis to generate two stem cells that are similar to its original cell state, thereby maintaining stem cell number.[2] This process of differentiation is …
Multipotent Mesenchymal Adult Stem Cells (MSCs)
Mesenchymal (MSC) derived stem cells are the bodies own restoration system. Nature allows MSC cells to deliver a homing signal that helps recruit other stem cells in the body to mobilize and “fix” an injured area. Researchers at Rosalind Franklin University of Medicine have recently reported that MSC Mesenchymal stem cells are much better prepared to begin the bodies natural …
Clonogenic Assay | Suspension Cells | Colony Formations
Clonogenic assay is otherwise also referred to as a “colony formation,” [1] this pertains to an in vitro process or survival analysis in order to determine a single cell’s capability to form a specific colony [2]. A colony refers to fifty cells or more. This process is particularly useful in analyzing the effects of ionization and cytotoxic agents upon the …
Iliac Crest Bone Marrow Aspiration and Grafting Site
The iliac crest is the prominent bony structure on the upper lateral part of the pelvis. It’s a common site for various medical procedures, including bone marrow biopsies and harvesting of stem cells. The bone marrow, which is found within the cavities of certain bones, including the iliac crest, is a primary source of stem cells, especially hematopoietic stem cells …





