Oligodendrocyte Marker Differentiation and Myelination

Regen Center Glossary

Oligodendrocytes are particular useful types of cell for treatment in conditions such as ataxia,brain injuries,ALS,motor neuron disease and spinal cord damage.
[1] Oligodendrocytes are also helpful for neural function in that it provides insulation through the myelin sheath.


For instance, in our treatments of autoimmune diseases like multiple sclerosis, considerable damage in the myelin sheath may be damaged, which exposes the neural cell underneath and impairs nerve signal transmission. [2]

Myelin Sheath Repair Video

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Published Clinical Citations

  • [1] ^ Mosebach, Jennifer, Gerburg Keilhoff, Tomasz Gos, Kolja Schiltz, Linda Schoeneck, Henrik Dobrowolny, Christian Mawrin, et al. 2013. Increased nuclear Olig1-expression in the pregenual anterior cingulate white matter of patients with major depression: a regenerative attempt to compensate oligodendrocyte loss? Journal of psychiatric research, no. 8 (April 21). doi:10.1016/j.jpsychires.2013.03.018. https://www.ncbi.nlm.nih.gov/pubmed/23615187

  • [2] ^ Pérez, María Julia, Natalia Fernandez, and Juana María Pasquini. 2013. Oligodendrocyte differentiation and signaling after transferrin internalization: a mechanism of action. Experimental neurology (June 21). doi:10.1016/j.expneurol.2013.06.014. https://www.ncbi.nlm.nih.gov/pubmed/23797152