Exomes are the portions of an organism’s genome containing protein-coding genes. They comprise a small part of the total DNA, usually around 1-2%, but are responsible for most known genetic functions. Exomes contain sequences called exons, which are the coding regions within genes. These exons are transcribed into RNA and then translated into proteins, which perform various functions within the …
Gene Therapy and the Future of Precision Medicine
Most traditional treatments today are designed using a one-size-fits-all to cover the “average” patient. But advances in biotechnology and Artificial intelligence (AI) medical researchers are now equipped with vast amounts of personalized datasets at their disposal, and can analyze unique situations based on our genetic profiles, family medical histories and other relevant medical conditions to better understand what types of …
Auto Paracrine Signaling Mechanism & Stem Cell Communication
What is Paracrine Communication? Paracrine signaling also known as Paracrine communication is a natural method of communication between cells that causes desired changes in surrounding cells and chemically altering the behavior surrounding cells. Why is paracrine signaling important? The paracrine communication system, exosomes and cytokines are critical for the success of functional medicine, regenerative medicine, and stem cell therapies. The …
Apoptosis and Programmed Cell Death “PCD”
There are generally 2 ways that human cells can die: They are destroyed through an injury or viral agent The cells induce themselves to commit suicide Cell Death through Injury or Harmful agents Cells in our bodies that have been damaged due to injuries, such as exposure to lethal/toxic chemicals or mechanical damage tend to go through a series of changes …
The Endothelial Cells & Endothelium Layer
Human Endothelial cells “EC” are estimated to account for nearly 1 kg of mass in the human body. This mass is about the same as our livers. Endothelial cells are thought to be produced by the splanchnopleuric mesoderm. These vital cells line the insides of all our blood vessels, including microscopic capillaries to larger arteries such as the aorta. The …