Stem cell research examines everything from gene expression to differentiation capacities to therapeutic potentials. With such diverse data types and complex experiments, researchers must determine the most appropriate statistical tests to analyze results. Parametric and nonparametric methods both play essential roles in stem cell data analysis. Parametric tests make assumptions about population parameters and rely on normally distributed data. Tests …
Intrathecal Delivery of Stem Cells in the Subarachnoid space
Stem cell therapy has emerged as a revolutionary new treatment approach for neurological and spinal disorders. One up-and-coming method of administering stem cells is an intrathecal application, which involves injecting the cells directly into the cerebrospinal fluid (CSF). This technique allows the stem cells to travel throughout the CSF and reach the brain and spinal cord, making it ideal for …
Wharton’s Jelly Mesenchymal Stem Cells (WJ-MSCs)
Wharton’s Jelly, a gelatinous substance found within the umbilical cord, is a rich mesenchymal stem cells (MSCs) source. These MSCs possess unique properties that make them a valuable tool in regenerative medicine, tissue engineering, and immunomodulation. Lets discuss some advantages and applications of Wharton’s Jelly stem cells along with methods used for extraction and utilization in clinical applications[1]. Clinical application …
The Angiogenesis Process and Its Therapeutic Benefits
Vascular enlargement, or angiogenesis, occurs when new blood vessels form inside the body’s preexisting vascular system. It begins in utero until old age, in health and sickness. A blood capillary, generated by the process of angiogenesis, is never more than a few hundred micrometres away from any metabolically active tissue in the body. All tissues rely on capillaries to facilitate …
Advantages & Future Applications of mRNA Technology
We recently experienced the powers of a ground-breaking vaccine against COVID-19 thanks to mRNA technology, but it has even more potential to democratize access to bleeding-edge medical advancements. Messenger RNA or “mRNA” is a single-stranded RNA involved in protein synthesis. Although the blueprint for proteins in living cells was discovered six decades ago, its pharmaceutical potential was long overlooked. mRNA …
Metronomic therapy
Metronomic therapy refers to the administration of low, continuous, and regular doses of certain drugs (often chemotherapeutic agents) without extended rest periods. This dosing strategy stands in contrast to the more traditional “maximum-tolerated dose” approach, where high doses of chemotherapy are given with intervening rest periods to allow for patient recovery from side effects. Features and benefits of metronomic chemotherapy: …