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Haploid Cell Function and Cellular Formation in Humans

A patient-focused guide to Haploid Cell Function and Cellular Formation in Humans, with clinical context, evaluation considerations and supporting information.

Human cells can be described by how many sets of chromosomes they carry. Almost all body cells are diploid, and only the egg and sperm cells (gametes) are haploid:

  1. Haploid cells
  2. Diploid cells

Haploid Vs Diploid

Video: Haploid Cell Function and Cellular Formation in Humans

Haploid cells pertains to the number of chromosomes found in a gamete or represents half of the normal chromosome count in a particular somatic cells. The primary difference between haploid and diploid cells are the total number of chromosomes they consist of.[1]

In humans, the haploid cells are the gametes. During meiosis, the homologous chromosome pairs separate in the first division and the sister chromatids separate in the second, producing 4 haploid daughter cells.[2]

When sex cells such as egg and sperm meet, the combined genetic material creates a full 46 chromosomes becoming diploid.Thus human Sexual reproduction is designed as a natural method of producing genetically diverse offspring.[3]

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Published Clinical Citations

[1] ^ Mahasup, Namfon, Paskorn Sritipsukho, Raweewan Lekskulchai, and Tippawan Hansakunachai. 2012. Effects of mirror neurons stimulation on motor skill rehabilitation in children with cerebral palsy: a clinical trial. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. https://www.ncbi.nlm.nih.gov/pubmed/23964461

[2] ^ Easley, Charles A, Bart T Phillips, Megan M McGuire, Jennifer M Barringer, Hanna Valli, Brian P Hermann, Calvin R Simerly, et al. 2012. Direct differentiation of human pluripotent stem cells into haploid spermatogenic cells. Cell reports, no. 3 (August 23). doi:10.1016/j.celrep.2012.07.015. https://www.ncbi.nlm.nih.gov/pubmed/22921399

[3] ^ Matangkasombut, Oranart, Roongtiwa Wattanawaraporn, Keiko Tsuruda, Masaru Ohara, Motoyuki Sugai, and Skorn Mongkolsuk. 2009. Cytolethal distending toxin from Aggregatibacter actinomycetemcomitans induces DNA damage, S/G2 cell cycle arrest, and caspase- independent death in a Saccharomyces cerevisiae model. Infection and immunity, no. 2 (December 7). doi:10.1128/IAI.00857-09. https://www.ncbi.nlm.nih.gov/pubmed/19995894