Sciatic nerve injury, Lumbar Radiculitis, and Sciatica pain usually result from sports injuries or other activities that compress the sciatic nerve. The pain can be severe and typically radiates from the lower back to the buttock and down the back of one leg, sometimes reaching the calf or foot. Pain in the shoulders or hands/wrists usually comes from the neck or local causes rather than the sciatic nerve. In most cases, pain and discomfort are transient and resolve within a few months, whereas some injuries persist. They may require surgery or alternative treatment options such as stem cell therapy.[1]
Stem Cell Therapy for Sciatica Nerve Injury
Sciatic pain is caused by many types of conditions, including:
- Bulging discs
- Chronic back injury
- Degenerative Disc Disease
- Slipped, Herniated, or ruptured disks
- Blunt Trauma from falling, causing nerve compression and a spinal compression fracture
- Sarcopenia musculoskeletal disease
- Ankylosing spondylitis, an inflammatory arthritis of the spine that belongs to the spondyloarthritis group and is distinct from rheumatoid arthritis and other inflammatory systemic autoimmune diseases
- Complex Regional Pain Syndrome, which can cause leg pain that is sometimes mistaken for sciatica
- Spinal stenosis & Spinal-related injuries
- Complications from Osteoporosis
- Shoulder injury caused by a torn rotator cuff
- Constriction of the piriformis muscle
- Femoral Neuropathy, which causes pain at the front of the thigh and is sometimes mistaken for sciatica
Using Stem Cells for Sciatic Nerve Injury
Sciatic nerve damage can sometimes improve over time, but recovery depends on the cause and severity, and some nerve injuries are permanent. Treatment options can be discussed with The Regeneration Center. The effects of peripheral neuropathy, Pinched nerves & sciatica can be damaging if left untreated. Conditions that can lead to this injury mainly involve the spine, which is primarily responsible for your movement and function. Others first show symptoms after a serious shoulder injury or damage to the hip joints, knee arthritis, and knee injuries. Imagine having to live a life with sciatic nerve injury and predisposing yourself to several distressing symptoms such as severe pain and muscle weakness, loss of mobility and sensation, and even loss of bowel or bladder control. New loss of bowel or bladder control, numbness in the groin or inner thighs, or rapidly worsening leg weakness can signal cauda equina syndrome and needs emergency medical care right away. Your quality of life would be significantly affected if sciatica is not adequately addressed and treated effectively with UC-MSC+ allogenic stem cells.
For this reason, persistent or worsening symptoms should be assessed by a doctor, although most sciatica improves with conservative care such as staying active, pain relief and physical therapy. Sciatica, or sciatic nerve impingement, can lead to permanent nerve damage from severe injuries or a prolonged, untreated condition.
Long-Term Results of UC-MSC+ Cell Therapy for Nerve Damage
The Role of Adult Stem Cells
Stem cells are unspecialized cells that can renew themselves and, depending on their type, develop into a limited or wider range of specialized cells. The stem cell therapy process requires adult stem cells, which differ significantly from embryonic cells. Using adult stem cells eliminates the arguments surrounding embryonic stem cell research. The adult cells used to treat chronic pain are called mesenchymal cells. These, in turn, can embrace the cell characteristic and assume the part, be it cartilage, bone, fat “adipose” cells, or nerve cells.
Motor nerve and muscle
The main parts of a motor neuron and its connections with muscle fibers.
Mesenchymal cells can come from the patient’s own fat tissue or bone marrow, or from donated umbilical cord tissue, which is the source used in the UC-MSC+ protocol described below. The harvested cells are then introduced into the injury site to grow and eventually rejuvenate the injured area. If the patient is in poor health and is not a candidate for autologous cell therapy, we can offer immune-compatible cells from cord tissue or placenta-derived cells.
Stem cell therapy is still considered the “last line of defense” to counter permanent nerve injury, as well as the resulting pain and disability for patients with lupus. This innovative regenerative medical treatment aims to bring light to the situation of patients with lingering chronic conditions or those who underwent conservative modalities such as physical therapy or spinal decompression, but without any favorable results.[2]
Non-Surgical Sciatic Nerve Treatment
If you want to relieve Sciatica without the risks of back surgery or steroid injections, a combination of expanded MSC+ stem cells may be a viable alternative. Our research experience has shown that most people with sciatica prefer not to have surgery or risk the long-term side effects experienced with frequent steroid injections. The Regeneration Center offers an investigational cell therapy that is being studied for its potential to support nerve and tissue repair, and it does not replace standard evaluation and care. Our UC-MSC+ sciatica protocol combines laboratory-expanded UC-MSC+ cells, neural progenitor cells, and nerve and tissue growth factors in a multi-stage treatment plan that will require 10-14 days in Bangkok.
The specifics of your SCIATICA protocol will depend entirely on the severity of the underlying condition and other relevant medical factors, such as your health and age. Contact us to determine whether stem cell therapy is appropriate for you, or to learn more about foods that may help with arthritis or how stem cells have helped people with sciatica.[3]
Cell sources and terminology
A guide to the source labels used in the laboratory illustration.
- Adipose tissue
ADSC
- Bone marrow
BM-MSC
- Peripheral blood
PB-MSC
- Placental tissue
P-MSC
- Umbilical cord
UC-MSC
- UC-MSC+
The Regeneration Center’s terminology used in this article.
Cost of Treating Sciatic Nerve Injury with UC-MSC+ Cells
The costs of treating sciatic nerve injuries depend on the extent of spinal or nerve damage. To begin the treatment evaluation, our orthopedic stem cell team will need to conduct a virtual consultation using your recent lab results (MRI, CT Scans) or a medical report from your primary care physician or orthopedic/spinal doctors in your home country. Upon completion of the therapy evaluation, a detailed treatment plan will be provided that includes the exact number of nights required and the total medical costs. To begin the qualification process for our multi-stage relief treatment for pinched nerves & Sciatica, please prepare your recent medical records contact us today.
Published Clinical Citations
[1] ^ Elfar JC, Jacobson JA, Puzas JE, Erythropoietin accelerates functional recovery after peripheral nerve injury. J Bone Joint Surg Am 2008;90:1644-53
[2] ^ The mesenchymal stem cell-derived microvesicles enhance sciatic nerve regeneration: a novel approach in peripheral nerve cell therapy.Raisi A, Azizi S, Delirezh N, Heshmatian B, Farshid AA, Amini K. J Trauma Acute Care Surg. 2014 Apr;76(4):991-7. doi: 10.1097/TA.0000000000000186.
[3] ^ Role of Central Plasticity in the Outcome of Peripheral Nerve Regeneration. Mohanty CB, Bhat D, Devi BI. Neurosurgery. 2015 Sep;77(3):418-23. doi: 10.1227/NEU.0000000000000851.