For thousands of years now, various cultures worldwide have developed unique practices to promote physical healing and wellness therapies known as integrative medicine. These ancient and traditional approaches to healthcare have included Ayurvedic medicine, Chinese medicine, traditional Thai medicine, acupuncture, yoga, herbal medications, meditation, and mind vs. body techniques that were holistic and usually looked beyond damage to the body by including the health of the body and spirit as well. Yet for most of the 19th and 20th centuries, western medicine ignored many of these holistic techniques and instead labeled them as tainted suspicious quackery.
In Western medical philosophy, disease is defined as the basis of the principal organ system in which symptoms and signs of infection are manifested and in which gross anatomic pathology and histopathology are correlated.[1] While this philosophy was instrumental in the early development stages of medical science, classifying diseases this way in the modern world would be unsuitable as it vastly overgeneralizes pathophenotypes and does not consider the preclinical disease manifestations and symptoms patients display. It also does not account for states of susceptibility and should not be used to individualize wellness therapies concerning chronic diseases.

In the last few decades, the emerging sciences of regenerative medicine and molecular medicine helped doctors develop a science-based understanding of how to incorporate integrative medical therapies so that they can be allowed to be applied in instances where the applications of traditional pharmaceutical-based medications failed. Old became new, and from these findings came the original concepts that helped coin the term functional medicine in the early 1990’s.
Functional medicine is a type of medical science that focuses primarily on interactions between the patient’s physical environment and bodily functions, such as between the endocrine, gastrointestinal, and immune systems. Functional medicine practitioners develop individualized treatment plans for the men, women, and children they treat. This paradigm shift takes healthcare with a disease-centric focus to one where we look at the relationships of the bodily systems and examine the whole person, not just a few of the isolated physical symptoms.
As technology advanced over the last 100 years, doctors became more reliant on pharmaceutical-based products, and physicians failed to understand the underlying issues and could no longer apply basic sciences in their practices. The medical industry became too concerned about categorizing the names of diseases and then implementing the appropriate drug protocols rather than spending the time needed to understand better the cause of the patient’s imbalances and underlying physiologic dysfunctions.
Functional healthcare management is like an operating system for the body that focuses on the structure and underlying causes of disease from a systemic biology perspective. It moves away from the histopathological definition of disease, which forcefully classified all medical dysfunctions into an insufficient number of descriptors.
Functional regenerative medicine operates on the notion that a person’s genome interacts with their lifestyle and environment. For several millennia, humanity has known that true wellness consists of mindfulness and daily lifestyle choices that are essential in helping to maintain optimal health and in treating illnesses and diseases. The most effective healthcare must balance organ-oriented, biomedical, cognitive, and interpersonal therapies.
Good health requires appropriately functioning biochemical and physiological processes, which operate as one process, whereas dysfunctional processes cause the symptoms known as sickness and illnesses.
Our stem cell institute believes that having good health is priceless and can be measured relatively easily via health checkups, body weight, and cardiovascular capacity, which lead to the goal of longevity. It is incumbent upon us to be deliberate and discerning in how we live our lives, how we use our time, how we use our energy, our attention, our finances, and most importantly, our relationships and whom we spend our time with to promote optimal long-term wellness.[3]
Advancements in recent biotechnologies and noninvasive screenings of cellular functions such as genomics, magnetic resonance imaging, transcriptomic analysis, biomarkers, metabolite profiling, and tests such as nuclear cardiac stress testing have provided doctors with new insight into the topology of biological networks. Before we had such technologies, complex diseases of unknown causes were labeled functional somatic disorders since the impaired biological functions were idiopathic and without any known organic or structural causes.[4]
This list of functional somatic disorders includes:
Regenerative medicine and MSC+ stem cell therapy are the future of healthcare and show great promise in bringing treatment modalities for people suffering from various diseases. Stem cell therapies, neural cell replacement, and tissue engineering are focused on delivering structural repair and functional restoration of the body systems and offer a radical shift from traditional surgical and pharma-based medical practices. Regenerative cellular treatment provides innovative solutions for patients looking to improve their quality of life, ranging from previously incurable congenital diseases and trauma due to spinal cord injuries, brain injuries, and heart attacks to degenerative conditions such as SLE, arthritis, DDD, Parkinson’s to Peripheral Neuropathy.
The regenerative model of healthcare we practice is predicated on a rigorous interdisciplinary approach that must be validated first by science and then translated into standardized clinical applications. Understanding the causes of disease and dysfunctions allows us to provide patient-centric care with a team of functional medicine practitioners trained for the safe and effective applications of global cellular regeneration therapies and wellness programs designed for longevity.
This is why monitoring early signs of liver disease and other organ-specific warning changes can be useful in functional medicine assessments, without replacing standard diagnostics.
On the other hand, functional medicine is considered a patient-centric approach. It relies less on merely naming the disease and more on understanding the causes early enough to correct the underlying issue more efficiently and give the patient the best possible chance to achieve positive outcomes. Patients displaying health issues in one organ system are seen as clues to a much more profound imbalance in the patient’s condition. Instead of isolating and focusing on the symptoms, our Functional Medicine doctors use specific tests to investigate all potential factors contributing to the poor results and look at the entirety of the patient’s medical history. This approach allows our medical team to understand better the complex interactions between the environmental, lifestyle choices, and genetic factors contributing to the patient’s poor health.[7]
With the proper medical information and tests, our functional medicine practitioners can spend time with patients, understand their histories, and look for the various interactions between the subject’s biochemical markers and genetic and environmental factors that influence chronic diseases and long-term health.
The Role of Genetics in Disease
Our Functional healthcare programs recognize the fact that nearly all health problems on earth come from two main factors:
For the most part, we do not have control over our genetic predispositions to particular diseases. Still, we can use the DNA data to identify genetic imprinting that led to built-in weak points to better control the influences in our surrounding environment. This awareness is a way to support the natural expression of genetics in a compelling way that we can use to manage, reduce, or prevent the occurrence of specific chronic diseases and factors such as Cardiometabolic risk. Chronic medical conditions include allergies, issues with digestion, malabsorption of nutrients, regulation of hormones and neurotransmitters, Inflammatory responses, Immune system dysfunctions, hormonal issues, metabolic issues, cognitive decline, and neurological problems. These are matters that most humans suffer from daily and can be reduced, improved, or eliminated by the proper use of Functional Medicine.
To learn more about Regenerative Functional medicine, please contact us today.
[1] ^ Bland, Jeffrey. Systems biology, functional medicine, and folates. Alternative therapies in health and medicine, no. 3. https://www.ncbi.nlm.nih.gov/pubmed/18517101
[2] ^ Bullmore, Ed. 2012. The future of functional MRI in clinical medicine. NeuroImage, no. 2 (January 12). doi:10.1016/j.neuroimage.2012.01.026. https://www.ncbi.nlm.nih.gov/pubmed/22261374
[3] ^ Cesario, Alfredo, Charles Auffray, Patrizia Russo, and Leroy Hood. 2014. P4 medicine needs P4 education. Current pharmaceutical design, no. 38. https://www.ncbi.nlm.nih.gov/pubmed/24641231
[4] ^ Chen, Fa-Ming, Yi-Min Zhao, Yan Jin, and Songtao Shi. 2011. Prospects for translational regenerative medicine. Biotechnology advances, no. 3 (November 27). doi:10.1016/j.biotechadv.2011.11.005. https://www.ncbi.nlm.nih.gov/pubmed/22138411
[5] ^ Henningsen, Peter, Stephan Zipfel, and Wolfgang Herzog. 2007. Management of functional somatic syndromes. Lancet (London, England), no. 9565 ( 17). https://www.ncbi.nlm.nih.gov/pubmed/17368156
[6] ^ Nicolaidis, Stylianos. 2012. Personalized medicine in neurosurgery. Metabolism: clinical and experimental (September 25). doi:10.1016/j.metabol.2012.08.022. https://www.ncbi.nlm.nih.gov/pubmed/23018147
[7] ^ Wessely, S, C Nimnuan, and M Sharpe. 1999. Functional somatic syndromes: one or many? Lancet (London, England), no. 9182 ( 11). https://www.ncbi.nlm.nih.gov/pubmed/10489969