Colorectal cancer also known as rectal cancer or bowel cancer occurs when abnormal cells grow out of control in the large intestine or rectum and form malignant tumours. Most colorectal cancers arise in the lining of the colon and rectum and form malignant tumors from benign polyps through different genetic mutations. Polyps are benign growths that are usually harmless. However, if it’s not detected and undiagnosed for a long time, it may become malignant.
Colorectal cancer includes a colon or rectal cancer, depending on the location and origin of the cancerous tumours. Colorectal cancera is one of the most common types of cancer in the world and the second leading cancer killer.
Nearly one-third of all colorectal cancers are believed to be caused by genetics and family history. The three most common genetic disorders associated with colorectal cancer are:
Colorectal cancer is staged and classified using the TNM system, which helps doctors understand your cancer.[1] TNM is:
Not everyone will experience symptoms of colorectal cancer. However, some common symptoms include:
Regular cancer screenings are essential for the early detection of bowel cancer in people with no signs or symptoms. The Regeneration Center recommends annual cancer screenings for all persons aged 48 to 80. Tests should include faecal occult blood tests to detect any blood particles (a potential symptom of colorectal cancer) in the stool.
For patients who have bowel cancer symptoms or are not fully diagnosed yet a comprehensive colorectal cancer screening will be necessary and can be done in Bangkok or outside of Thailand.
Colonoscopy: A colonoscopy exam is a procedure in which a tube with a camera attached to the rectum is inserted into the rectum to examine the entire length of the colon. Colonoscopy is most commonly used to diagnose severe iron deficiency anaemia and patients with mild bowel symptoms. This test has both diagnostic and therapeutic uses. It can take tumour biopsies, stop tumour bleeding, and place stents to relieve blockages.
CT Scan or Computed Tomography Colonography – Computed Tomography Colonography, also known as virtual colonoscopy. It provides a less invasive examination for those who cannot undergo colonoscopy by utilizing 3D images of the large intestine and rectum produced by a computed tomography scanner. However, colonoscopy tests may still be required if a biopsy is required. If the CT Scan results lead to a diagnosis of ulcerative colitis or bowel cancer, additional tests are usually done to assess whether cancer has spread beyond the colon or rectum.[3]
Other checks can include:
There are many treatments available for colorectal cancer, and our treatment plans are customized to you and your cancer. Immunotherapy treatment options for colorectal cancer depend on the cancer type, tumour size, stage, location, health, and treatment preferences. One of the most common traditional treatment for colorectal cancer is surgery, depending on the cancer stage. It can be used with chemotherapy, radiation therapy or targeted therapy.
Cancer Surgery – A surgical procedure can be used to treat colorectal cancer is known as a colorectal resection (colectomy). Colon resection surgery requires removal of all or
Our integrative approach to dealing with cancers uses a variety of techniques alone or as Adjuvant immunotherapies including:
Our team of cellular oncologist have over 50 years of experience dealing with cancers and the immune system. The holistic cancer treatment and NK cell protocols we provide offer unique bio-
Traditional cancer treatments such as chemotherapy & radiation therapy expose humans to significant side effects and toxicity. Over time, the traditional methods have not changed but the cancer cells themselves have evolved making them more resistant to the chemicals and rendering these traditional therapies ineffective especially in later stages of kidney cancer, lung cancer, prostate cancer pancreatic adenocarcinoma and hepatocellular carcinoma. This evolution of cancer stem cells is what leads to recurrence and allows them to proliferate much more aggressively than before the chemo & radiation therapies began decades ago. Some new pharmaceutical based medications have been developed to effectively target and destroy cancer cells with much less toxicity, but the payloads often don’t reach the intended destinations and are consumed but the patients immune system before it can reach the intended targets and tumors.
A tightly integrated approach in the treatment of bowel cancer, our cancer stem cell treatments continue to improve remission rates year after year. With new discoveries in pancreatic cancer research, clinical trials for new protocols to more effectively treat stage 1 – stage 4 colorectal cancer. The Regen Center is a pioneer in regenerative medicine and are able to apply new bioengineering techniques to better manage malignant tumors and to help our patients live a cancer-free life, with minimal toxicity and without fear of remission.
To determine eligibility and treatment opinions from our immunotherapy team we will need to better understand the patient’s existing needs via recent histological results, Biopsy scans, blood tests, x-rays, scans, bone marrow sample results and/or clinical diagnosis documents from your primary care oncologist.
Being diagnosed with the big “C” does not have to be the last stand. Even if traditional cancer treatments options have reached their limits, Our team can still offer options that bring you one step closer to the latest treatment for rectal cancer and living a cancer-free life. We are here to help you and your family get past the disease using safe and research-based alternative treatment options for treating cancer of the bowel. To learn more please contact us today.
[1] ^Siripongpreeda B, Mahidol C, Dusitanond N, Sriprayoon T, Muyphuag B, Sricharunrat T, Teerayatanakul N, Chaiwong W, Worasawate W, Sattayarungsee P, Sangthongdee J, Prarom J, Sornsamdang G, Soonklang K, Wittayasak K, Auewarakul CU. High prevalence of advanced colorectal neoplasia in the Thai population: a prospective screening colonoscopy of 1,404 cases. BMC Gastroenterol. 2016 Aug 23;16(1):101. doi: 10.1186/s12876-016-0526-0. PMID: 27553627; PMCID: PMC4995664.
[2] ^Fan J, Shang D, Han B, Song J, Chen H, Yang JM. Adoptive Cell Transfer: Is it a Promising Immunotherapy for Colorectal Cancer? Theranostics. 2018 Nov 10;8(20):5784-5800. doi: 10.7150/thno.29035. PMID: 30555581; PMCID: PMC6276301.
[3] ^Alsadhan N, Almaiman A, Pujades-Rodriguez M, Brennan C, Shuweihdi F, Alhurishi SA, West RM. A systematic review of methods to estimate colorectal cancer incidence using population-based cancer registries. BMC Med Res Methodol. 2022 May 19;22(1):144. doi: 10.1186/s12874-022-01632-7. PMID: 35590277; PMCID: PMC9118801.
[4] ^Du W, Frankel TL, Green M, Zou W. IFNγ signaling integrity in colorectal cancer immunity and immunotherapy. Cell Mol Immunol. 2022 Jan;19(1):23-32. doi: 10.1038/s41423-021-00735-3. Epub 2021 Aug 12. PMID: 34385592; PMCID: PMC8752802.
[5] ^Silva VR, Santos LS, Dias RB, Quadros CA, Bezerra DP. Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells. Cancer Commun (Lond). 2021 Dec;41(12):1275-1313. doi: 10.1002/cac2.12235. Epub 2021 Nov 17. PMID: 34791817; PMCID: PMC8696218.