An Ectoderm is a body of cells forming the outermost layer of major organ systems in the body, such as the skin, neural cells and nervous system, and the sensory organs. This layer is formed by the blastocyst’s inner cell mass.[1]
The cells of various germ layers can differentiate themselves [2] through lab culturing to try to regenerate and repair diseased organs and dysfunctioning systems in the body through a process known as organogenesis.
The ectoderm layer can also give rise to a person’s:
During embryonic development, the embryo undergoes gastrulation, forming three primary germ layers: ectoderm, mesoderm, and endoderm. These germ layers give rise to various tissues and organs in the developing organism.
The ectoderm is the outermost germ layer. It differentiates to form a wide variety of tissues and structures, including:
The endoderm is the innermost germ layer and differentiates to form the lining of many internal structures, as well as certain glands:
Understanding the derivatives of the germ layers is fundamental in developmental biology. It helps scientists and medical professionals predict and understand congenital anomalies and the embryonic origin of various tissues and organs.
[1] ^ Pieper, Mareike, Katja Ahrens, Elke Rink, Annette Peter, and Gerhard Schlosser. 2012. Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm. Development (Cambridge, England), no. 6 (February 8). doi:10.1242/dev.074468. https://www.ncbi.nlm.nih.gov/pubmed/22318231
[2] ^ Yardley, Nathan, and Martín I García-Castro. 2012. FGF signaling transforms non-neural ectoderm into neural crest. Developmental biology, no. 2 (September 19). doi:10.1016/j.ydbio.2012.09.006. https://www.ncbi.nlm.nih.gov/pubmed/23000357
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