.sct-gene-panel {
  --gene-ink: #10343a;
  --gene-muted: #5d7376;
  --gene-teal: #087e80;
  --gene-teal-deep: #075d68;
  --gene-line: #cbd8d5;
  position: relative;
  isolation: isolate;
  width: 100%;
  margin: clamp(2.5rem, 6vw, 4.75rem) 0;
  overflow: hidden;
  overflow: clip;
  border: 1px solid var(--gene-line);
  border-radius: clamp(1.25rem, 2.5vw, 1.8rem);
  background:
    radial-gradient(circle at 91% 3%, rgba(8, 126, 128, 0.12), transparent 21rem),
    linear-gradient(148deg, #fbfdfc, #eef6f3);
  box-shadow: 0 1.25rem 3.8rem rgba(18, 62, 67, 0.09);
  color: var(--gene-ink);
  font: inherit;
}

.sct-egfr + .sct-gene-panel {
  margin-top: 0;
}

.sct-gene-panel::after {
  position: absolute;
  z-index: -1;
  inset: auto -6rem -8rem auto;
  width: 18rem;
  height: 18rem;
  border: 1px solid rgba(8, 126, 128, 0.09);
  border-radius: 50%;
  box-shadow:
    0 0 0 2.2rem rgba(8, 126, 128, 0.025),
    0 0 0 4.4rem rgba(8, 126, 128, 0.018);
  content: "";
  pointer-events: none;
}

.sct-gene-panel *,
.sct-gene-panel *::before,
.sct-gene-panel *::after {
  box-sizing: border-box;
}

.sct-gene-panel__head {
  display: grid;
  gap: 1.3rem;
  padding: clamp(1.4rem, 3.4vw, 2.3rem);
  border-bottom: 1px solid rgba(139, 164, 161, 0.42);
}

.sct-gene-panel__identity {
  display: flex;
  min-width: 0;
  align-items: center;
  gap: 1rem;
}

.sct-gene-panel__mark {
  display: grid;
  flex: 0 0 4rem;
  width: 4rem;
  height: 4rem;
  grid-template-columns: 1fr 1fr;
  place-items: center;
  overflow: hidden;
  border: 1px solid rgba(8, 126, 128, 0.23);
  border-radius: 1.15rem;
  background: rgba(255, 255, 255, 0.78);
  box-shadow: 0 0.8rem 2rem rgba(18, 73, 73, 0.08);
  color: var(--gene-teal-deep);
}

.sct-gene-panel__mark span {
  display: grid;
  width: 100%;
  height: 100%;
  place-items: center;
  border-right: 1px solid rgba(153, 177, 173, 0.3);
  border-bottom: 1px solid rgba(153, 177, 173, 0.3);
  font-size: 0.65rem;
  font-weight: 850;
  letter-spacing: 0.04em;
}

.sct-gene-panel__mark span:nth-child(even) {
  border-right: 0;
}

.sct-gene-panel__mark span:nth-child(n + 3) {
  border-bottom: 0;
}

.sct-gene-panel__eyebrow,
.sct-article-content .sct-gene-panel .sct-gene-panel__eyebrow {
  margin: 0 0 0.35rem;
  color: var(--gene-teal-deep);
  font-size: 0.67rem;
  font-weight: 820;
  letter-spacing: 0.13em;
  line-height: 1.3;
  text-transform: uppercase;
}

.sct-gene-panel h2,
.sct-article-content .sct-gene-panel h2,
.sct-template-therapy .sct-article-content .sct-gene-panel h2 {
  margin: 0;
  color: var(--gene-ink);
  font-size: clamp(1.65rem, 3.8vw, 2.7rem);
  font-weight: 670;
  letter-spacing: -0.045em;
  line-height: 1.05;
  text-align: start;
  text-wrap: balance;
}

.sct-gene-panel h2[id] {
  scroll-margin-top: calc(var(--sct-reading-offset, 7.5rem) + 2.5rem);
}

.sct-article-content .sct-gene-panel h2[id][tabindex="-1"] {
  scroll-margin-top: calc(var(--sct-reading-offset, 7.5rem) + 2.5rem);
}

.sct-gene-panel h2[id]:focus {
  outline: none;
}

.sct-gene-panel h2[id]:focus-visible {
  outline: 2px solid var(--gene-teal);
  outline-offset: 0.3rem;
}

.sct-gene-panel__count {
  display: grid;
  width: 6.2rem;
  min-height: 6.2rem;
  place-content: center;
  justify-self: start;
  border: 1px solid rgba(8, 126, 128, 0.22);
  border-radius: 50%;
  background: rgba(255, 255, 255, 0.75);
  box-shadow:
    inset 0 0 0 0.6rem rgba(8, 126, 128, 0.035),
    0 0.8rem 2.1rem rgba(18, 73, 73, 0.07);
  text-align: center;
}

.sct-gene-panel__count strong {
  color: var(--gene-teal-deep);
  font-size: 2rem;
  font-variant-numeric: tabular-nums;
  font-weight: 680;
  letter-spacing: -0.06em;
  line-height: 0.95;
}

.sct-gene-panel__count span {
  max-width: 4.5rem;
  margin-top: 0.35rem;
  color: var(--gene-muted);
  font-size: 0.56rem;
  font-weight: 760;
  letter-spacing: 0.07em;
  line-height: 1.2;
  text-transform: uppercase;
}

.sct-gene-panel__intro,
.sct-article-content .sct-gene-panel .sct-gene-panel__intro {
  max-width: 62rem;
  margin: 0;
  padding: clamp(1.35rem, 3vw, 2rem) clamp(1.4rem, 3.4vw, 2.3rem) 0;
  color: #405d61;
  font-size: 0.93rem;
  line-height: 1.72;
}

.sct-gene-panel__resource,
.sct-article-content .sct-gene-panel .sct-gene-panel__resource {
  margin: 0;
  padding: 0.75rem clamp(1.4rem, 3.4vw, 2.3rem) 0;
  font-size: 0.78rem;
  line-height: 1.5;
}

.sct-article-content.w-richtext .sct-gene-panel .sct-gene-panel__resource a,
.sct-gene-panel .sct-gene-panel__resource a {
  color: var(--gene-teal-deep);
  font-size: inherit;
  font-weight: 760;
  line-height: inherit;
  text-underline-offset: 0.2em;
}

.sct-gene-panel__index {
  margin: clamp(1.3rem, 3vw, 2rem) clamp(1.4rem, 3.4vw, 2.3rem);
  padding: clamp(1rem, 2.5vw, 1.4rem);
  border: 1px solid rgba(151, 174, 170, 0.55);
  border-radius: 1.15rem;
  background: rgba(255, 255, 255, 0.72);
}

.sct-gene-panel__index-head {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  gap: 1rem;
  margin-bottom: 0.9rem;
}

.sct-gene-panel__index-head strong {
  color: var(--gene-ink);
  font-size: 0.77rem;
  font-weight: 800;
  letter-spacing: 0.06em;
  text-transform: uppercase;
}

.sct-gene-panel__index-head span {
  color: var(--gene-muted);
  font-size: 0.65rem;
}

.sct-gene-panel__genes,
.sct-article-content .sct-gene-panel .sct-gene-panel__genes {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(6.2rem, 1fr));
  gap: 0.48rem;
  margin: 0;
  padding: 0;
  list-style: none;
}

.sct-gene-panel__genes li,
.sct-article-content .sct-gene-panel .sct-gene-panel__genes li {
  min-width: 0;
  margin: 0;
  padding: 0;
}

.sct-gene-panel__genes code {
  display: grid;
  min-height: 2.35rem;
  place-items: center;
  overflow: hidden;
  padding: 0.5rem 0.55rem;
  border: 1px solid #d5dfdd;
  border-radius: 0.72rem;
  background: #f8fbfa;
  color: #244c50;
  font-family: inherit;
  font-size: 0.67rem;
  font-weight: 790;
  letter-spacing: 0.035em;
  line-height: 1.2;
  text-align: center;
  text-overflow: ellipsis;
  white-space: nowrap;
}

.sct-gene-panel__more {
  margin-top: 0.7rem;
}

.sct-gene-panel__more > summary {
  display: flex;
  min-height: 2.65rem;
  align-items: center;
  justify-content: space-between;
  gap: 1rem;
  padding: 0.55rem 0.75rem;
  border: 1px solid #d3dddb;
  border-radius: 0.78rem;
  background: #edf5f2;
  color: var(--gene-teal-deep);
  cursor: pointer;
  font-size: 0.7rem;
  font-weight: 780;
  line-height: 1.35;
  list-style: none;
}

.sct-gene-panel__more > summary::-webkit-details-marker {
  display: none;
}

.sct-gene-panel__more > summary span:last-child {
  display: grid;
  flex: 0 0 1.6rem;
  width: 1.6rem;
  height: 1.6rem;
  place-items: center;
  border: 1px solid rgba(8, 126, 128, 0.2);
  border-radius: 50%;
  background: #fff;
  transition: transform 180ms ease;
}

.sct-gene-panel__more[open] > summary span:last-child {
  transform: rotate(45deg);
}

.sct-gene-panel__genes--additional {
  margin-top: 0.65rem;
}

.sct-gene-panel__note,
.sct-article-content .sct-gene-panel .sct-gene-panel__note {
  display: flex;
  align-items: flex-start;
  gap: 0.7rem;
  margin: 0;
  padding: 0 clamp(1.4rem, 3.4vw, 2.3rem) clamp(1.45rem, 3.4vw, 2rem);
  color: var(--gene-muted);
  font-size: 0.72rem;
  line-height: 1.6;
}

.sct-gene-panel__note > span:first-child {
  display: grid;
  flex: 0 0 1.6rem;
  width: 1.6rem;
  height: 1.6rem;
  place-items: center;
  border: 1px solid rgba(8, 126, 128, 0.22);
  border-radius: 50%;
  color: var(--gene-teal-deep);
  font-size: 0.66rem;
  font-style: normal;
  font-weight: 850;
}

.sct-article-content.w-richtext .sct-gene-panel .sct-gene-panel__note a,
.sct-gene-panel .sct-gene-panel__note a {
  margin-inline-start: 0.25rem;
  color: var(--gene-teal-deep);
  font-size: inherit;
  font-weight: 760;
  line-height: inherit;
}

@media (min-width: 680px) {
  .sct-gene-panel__head {
    grid-template-columns: minmax(0, 1fr) auto;
    align-items: center;
  }

  .sct-gene-panel__count {
    justify-self: end;
  }
}

@media (max-width: 480px) {
  .sct-gene-panel h2[id],
  .sct-article-content .sct-gene-panel h2[id][tabindex="-1"] {
    scroll-margin-top: calc(var(--sct-reading-offset, 7.5rem) + 2.5rem);
  }

  .sct-gene-panel h2[id]::before {
    display: block;
    height: 3.5rem;
    margin-top: -3.5rem;
    content: "";
    visibility: hidden;
  }

  .sct-gene-panel__identity {
    align-items: flex-start;
  }

  .sct-gene-panel__mark {
    flex-basis: 3.35rem;
    width: 3.35rem;
    height: 3.35rem;
    border-radius: 0.95rem;
  }

  .sct-gene-panel__count {
    width: 5.4rem;
    min-height: 5.4rem;
  }

  .sct-gene-panel__index-head {
    align-items: flex-start;
    flex-direction: column;
    gap: 0.2rem;
  }

  .sct-gene-panel__genes,
  .sct-article-content .sct-gene-panel .sct-gene-panel__genes {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }
}

@media (prefers-reduced-motion: reduce) {
  .sct-gene-panel *,
  .sct-gene-panel *::before,
  .sct-gene-panel *::after {
    transition-duration: 0.001ms;
    animation-duration: 0.001ms;
  }
}